Items Listed In The Telomeres Category:
The Role of Telomeres in Aging and Cancer
Telomeres are small stretches of DNA at each end of every chromosome that shorten with each replication until the chromosome is unable to replicate further. This may be a cause of aging, since cells with chromosomes whose telomeres are depleted will not be able to replicate to replace dying cells. In cancer, a chemical called telomerase helps rebuild the telomeres, allowing the cells to reproduce out of control.
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Triple Helix in Telomerase Structure Described
Telomeres and telomerase are important factors for understanding both aging
and cancer. While the molecular makeup of telomerase has been known for some years,
the physical structure is less well understood. This is the first major piece of
telomerase for which the structure is known, and it shows a surprising triple helix shape.
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