Description of Coenzyme Q10The National Cancer Institute published this description of coenzyme Q10, describing its function in the body, and reviewing the sparse medical literature available on the chemical's effect on cancer. First identified in 1957, coenzyme Q10 (also known as CoQ10, Q10, vitamin Q10, ubiquinone, or ubidecarenone) is made in the human body, and tends to decrease with age. As a coenzyme it is required for the proper functioning of other enzymes. It is used by cells to produce energy, and it acts as an antioxident. It also stimulates the immune system. There have been few laboratory studies or clinical trials involving coenzyme Q10, but those have been generally positive. It has been shown to reduce damage to the heart when using the anticancer drug doxorubicin. A poorly designed study in Denmark suggests that it helps cancer patients undergoing standard treatments. That study was not very reliable, but is suggestive. In a followup study, one new patient and one of the patients who had a reported remission were treated with high doses of coenzyme Q10 for 3 to 4 months. Both of the patients had breast cancer remaining after surgery. After the period of high-dose coenzyme Q10 supplementation, both patients appeared to experience complete regression (decrease in the size or extent) of their remaining cancer. However, it is not known which of the six patients with a reported remission in the first study took part in the followup study. There are also anecdotal reports that coenzyme Q10 has been beneficial in treating cancer patients. There have been no serious side effects reported from the use of coenzyme Q10 supplements, though a series of minor complaints from users suggests that there probably is an upper limit to safe dosage -- what that may be remains unknown. If you have had any experience with this supplement, use the Add Comment link at the right and share your observations! |
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